Advance In-Vivo Activities of Polyherbal Formulations (Foeniculum Vulgare, Emblica Officinalis and Ocimum Sanctum) with Different Pharmacological Studies

Abstract

Herbal products with potential therapeutic and nutritional values are gaining importance among people around the world. Herbal products are typically regarded as safe for use on humans. The preparation and marketing of extracts from various herbal items or purified bioactive components takes many different forms. Products with more than two herbal extracts are called polyherbal products. They are frequently regarded as prophylactically or therapeutically useful due to their complimentary and/or potentiating functions as a result of the advantages of one another. The phytochemical screening was performed for presence of various phytoconstituents. Our interest was to study the effect of polyherbal formulation (PHF), composed of Foeniculum vulgare, Emblica officinalis and aerial part of Ocimum sanctum. The anxiolytic activity of polyherbal formulations were examined by using the elevated plus maze test (EPMT), open field test (OFT), and motor coordination test assessed by Rota rod test (RT) and hole board test (HST). The present study is designed to evaluate the Acute toxicity studies, anti-stress effect and anti-anxiety effect of extract of Foeniculum vulgare, Emblica officinalis and aerial part of Ocimum sanctum using various experimental models in rodents. A current investigation concluded that PHF exhibited a strong anti-stress effect and anti-anxiety effect.