Metallopharmaceuticals Compound -Past Lessons And Future Directions -A Review
Main Article Content
Abstract
This article is an overview that discusses the history, chemistry, synthesis, prospects, and applications of Schiff bases and related metal compounds. This provides an update on recent facts regarding Schiff's performance, which consisted of a variety of challenging elements. The field of therapeutic inorganic chemistry lies at the crossroads of medicine and inorganic chemistry. It consists of metal-based drugs, professionals who can sequester and mobilise metal, and demonstrative aids that contain metal. Drugs that are formed of organometallic compounds have been used for the treatment of a wide variety of ailments for many years. At the level of individual atoms, the following metal elements play significant roles in the architecture of living organisms: When antimicrobial drugs interact with particular metal particles, the drugs might become more effective against microbes. It is possible to enhance the activity of bioactive molecules by utilising coordination compounds that contain metal. In this article, several different applications of metals in biological systems will be discussed in depth.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
Boulechfar C, Ferkous H, Delimi A, Djedouani A, Kahlouche A, Boublia A, Darwish A.S, Lemaoui T, Verma R and Y. Benguerba: Schiff bases and their metal Complexes: A review on the history, synthesis, and applications, Inorganic Chemistry Communications 2023; 150:110451.
Sanjanwala D and Patravale V: Aptamers and nanobodies as alternatives to antibodies for ligand-targeted drug delivery in cancer, Drug Discovery Today 2023; 28:103550.
Wang Y and Guo N: A new photoluminescent Zn(II) complex and its therapeutic effect on lung cancer, Inorganic and Nano-Metal Chemistry 2022; 1–6.
L. H. Khoi, L. T. H. Thom and P. T. Tien, Components of the Space of Weighted Composition Operators Between Different Fock Spaces in Several Variables, Mediterranean Journal of Mathematics; 20 ;(2023).
S. Bi, J. Qi, W. Zhang and X. Jiang, Liquid Metal Dressing for Anti-inflammation and Anti-infections to Treat Diabetic Wound, Chemical Communications (2023).
M. Alwash and N. Jaber, Trace elements (selenium, copper and zinc) in de novo acute leukemia: serum levels and their relation with some clinical and laboratory parameters, Iraqi Journal of Hematology ;12; (2023); 105.
R. Katturajan and S. Evan Prince, L-carnitine and Zinc supplementation impedes intestinal damage in methotrexate-treated adjuvant-induced arthritis rats: Reinstating enterocyte proliferation and trace elements, Journal of Trace Elements in Medicine and Biology 78 (2023) 127188.
D. Valencia, Chemical bonding and aromaticity analyses of petroporphyrins with vanadium or nickel, Fuel ;333; (2023); 126344.
M. K. Wojnar, J. W. Ziller and A. F. Heyduk, Two-Electron Mixed Valency in a Heterotrimetallic Nickel–Vanadium–Nickel Complex, Inorganic Chemistry ;62 ;(2023) 1405–1413.
M. M. Samra and M. A. R. Basra, Synthesis, spectroscopic, in vitro, in vivo biological evaluation, and in silico docking analysis of new meloxicam metal complexes, Applied Organometallic Chemistry ;37 ;(2023).
X. Huang, Q.-K. Shen, H.-Y. Guo, Z.-S. Quan and X.-T. Li, Research, Development and Pharmacological Activity of Fusidic acid and its derivatives, Journal of Molecular Structure (2023) 135942.
M. A. Mahmood, Pharmacological Action of Taxifolin: A Review, Open Access Journal of Pharmaceutical Research ;7; (2023), 1-5
13.S. Mor and M. Khatri, Convenient synthesis of benzothiazinoisoindol-11-ones and benzoindenothiazin-11-ones, and antimicrobial testing thereof, Molecular Diversity;27 (2022); 1223–1241.
Complex parts from nature, Metal Powder Report ;78; (2023),1-4.
SUZUKI, T. K. (2021). Biological Physics in Phenotypic Systems of Living Organisms. Seibutsu Butsuri, 61(1), 031–035. https://doi.org/10.2142/biophys.61.031
Mark Peplow, special to C&EN. (2021, May 16). Catalytic patch activates cancer drug while avoiding side effects. Chemical & Engineering News, 7–7.
Pak, V. (2022). Alpha-Fetoprotein Binds Toxins and Can Be Used to Treat Cancer. Medical Research Archives, 10(10).
Shumi, G., Desalegn, T., Demissie, T. B., Ramachandran, V. P., & Eswaramoorthy, R. (2022, May 17). Metal Complexes in Target-Specific Anticancer Therapy: Recent Trends and Challenges. Journal of Chemistry, 2022, 1–19. .
Hindawi, Shumi G, Desalegn T, et al. Metal Complexes in Target-Specific Anticancer Therapy: Recent Trends and Challenges [Internet]. Metal Complexes in Target-Specific Anticancer Therapy: Recent Trends and Challenges, 2022.
Kurdi, F., Abidin, Z., Priyanti, R. P., & Kholis, A. H. (2021, October 27). Management Of Diabetes Mellitus Type 2 For Elderly: Taichi Exercise To Reduce Blood Sugar Levels. Nursing and Health Sciences Journal (NHSJ), 1(2), 112–117.
Once-Weekly Insulin for Type 2 Diabetes without Previous Insulin Treatment. (2021, February 25). New England Journal of Medicine, 384(8), e26.
Sharma, P., Hajam, Y. A., Kumar, R., & Rai, S. (2022, February). Complementary and alternative medicine for the treatment of diabetes and associated complications: A review on therapeutic role of polyphenols. Phytomedicine Plus, 2(1), 100188.
Preeti S., Younis Ahmad H., Rajesh K., Seema R; Complementary and alternative medicine for the treatment of diabetes and associated complications: A review on therapeutic role of polyphenols; Phytomedicine Plus, 2, 1, 2022, 100188.
Marshes Research Center, I., Kadhem, B., Alshawi, J., Kadhema, B., & abdalla, M. (2021, December 12). Novel Schiff Bases Ligands and Their Complexes: Thermal Analysis, Antibacterial Activity, and Molecular Docking. Egyptian Journal of Chemistry, 0(0), 0–0.
Van de Walle T., Briand M., Mitrović A., Sosič I., Gobec S., Kos J., Persoons L., Daelemans D., De Jonghe S., Ubiparip Z., et al. Synthesis of Novel Nitroxoline Analogs with Potent Cathepsin B Exopeptidase Inhibitory Activity. Chem. Med. Chem. 15: ,(2020), 2477–2490
Schmiermund, T.,Acid-Base Theories. In: The Chemistry Knowledge for Firefighters.
Springer, Berlin, Heidelberg,(2023).
Irena Kostova, The Role of Complexes of Biogenic Metals in Living Organisms;
Inorganics, 11(2), 56; (2023).
Çetin Z, Dede B. A novel Schiff base ligand and its metal complexes: Synthesis,
characterization, theoretical calculations, catalase-like and catecholase-like enzymatic
activities. Journal of Molecular Liquids Elsevier BV; 2023; 380, 121636.
Yin L, Zhang S, Zhou T, Zhen’guang H, Zhang S. Synthesis, characterization, and anticancer activity of mononuclear Schiff-base metal complexes. Journal of Molecular Structure Elsevier BV; 2023; 1275 : 134683
Malav R, Ray S. Carbon-carbon cross coupling reactions assisted by Schiff base complexes of Palladium, cobalt and copper: A brief overview. Inorganica Chimica Acta Elsevier BV; 2023; 551 :121478.
Bhandarkar SE, Pathare PP, Khobragade BP. New Nickel (II), Copper (II) and Cobalt (II)
Complexes Based Salicyaldehyde Schiff Base: Synthesis, Characterisation, and Antiviral
Activity. Materials Today: Proceedings Elsevier BV; 2023,1-5.
D. venkatachalam, A review on herbal cosmetics used in skin and hair care. International
Research Journal of Modernization in Engineering Technology and Science; 2023,120-125.
Wei S, Hou X, Liu L, Tian Y, Li W, Xu H. Improving the Adsorption Properties of Keratin-
Based Goat Hair Toward Reactive Dyes in Dyeing Wastewater by Steam Explosion. Journal of Natural Fibers Informa UK Limited; 2022; 20.
Manaka T, Otoshima A. Improving hydrogen embrittlement resistance of an Al-Zn-Mg-Cu alloy by retrogression and re-aging treatment. Journal of Japan Institute of Light Metals Japan Institute of Light Metals; 2023; 73 : 205–11.