The Effect of Individual Characteristics and Role of Social Environment on Drug Resistant Tuberculosis Patient’s Adherence Treatment during Pandemic COVID-19 Era

Abstract

Drug Resistant Tuberculosis (DR TB) continues to be a threat to society. The increasing number of treatments drop out will lead to high mortality and Lost To Follow Up (LTFU). Therefore, it is necessary to analyze more deeply about treatment adherence influencing factors, starting from individual internal and external factors to social environment factors.

Method: This quantitative study used a cross-sectional design toward 156 both on patients and ex-patients who had recovered from DR TB in Special Region of Yogyakarta and Central Java.

The sampling technique used was purposive sampling. The data was collected through a valid and reliable questionnaire valued > 0.444 per questions (r count > r table) in 20 patients. The data was analyzed in bivariate using Chi Square and multivariate using Logistic Regression through Stata application.

Result: The result of bivariate test showed the influencing factors are age, knowledge, motivation, socioeconomic, occupation, family support, social support and stigmatization with value p > 0.05. While factors that are not influencing the treatment adherence are education (p=0.153) and sociodemographic (p=0.782). The result of multivariate analysis stated family support provided the highest chance of treatment adherence (OR 27.9)

Conclusion: Individual internal factors (age, knowledge, and motivation), individual external factors (socioeconomic and occupation), and social environment factors (family support, social support, and stigmatization) are affecting the medical adherence in DR TB patients that and lead to high recovery chance.